In recent years, Devon Expressway derbies between Plymouth Argyle and Exeter City have been played when the Pilgrims have either been in financial turmoil, or in Administration.
However, ahead of this Saturday's meeting at Home Park, the Grecians have been under a transfer embargo - as a result of an outstanding loan to the PFA- which left City boss Paul Tisdale unable to make any close season signings.
Also a bout of illness and several injuries within his squad forced Tisdale to come out of retirement and re-register himself as a player, and he named himself amongst the substitutes on their opening day of the season encounter with Portsmouth.
The embargo has since been lifted and Tisdale has added former Preston North End striker Graham Cummins to his squad, following a successful trial spell, and the Irishman is set to make his debut against the Pilgrims.
Argyle, on the other hand, will be looking to take the momentum from their 6-5 penalty shoot-out defeat at the hands of last season's losing League One Play-Off finalists Leyton Orient (the Pilgrims drew 3-3 in normal time).
After losing away at Cambridge United on the opening day, manager John Sheridan will no doubt see regard a positive performance and result against the Grecians as a must as Argyle aim to improve on last season's 10th place finish, and mould a side capable of mounting a challenge for promotion.